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Ulcerative Colitis clinical trials recruiting in the U.S.
80 studies for Ulcerative Colitis are recruiting participants at sites across the United States.
Ulcerative Colitis (UC) can cause long-lasting swelling and ulcers in the large intestine. It is a type of inflammatory bowel disease. Find out more.
Cities with the most studies
- New York City, NY24 studies
- Miami, FL22 studies
- Orlando, FL22 studies
- Houston, TX17 studies
- San Antonio, TX16 studies
- San Diego, CA15 studies
- Chicago, IL15 studies
- Tacoma, WA14 studies
- Colorado Springs, CO14 studies
- Tyler, TX13 studies
- Los Angeles, CA13 studies
- St. Louis, MO13 studies
- Washington, DC12 studies
- Boston, MA12 studies
- Cincinnati, OH11 studies
- Durham, NC11 studies
- Tampa, FL10 studies
- Providence, RI10 studies
- Louisville, KY10 studies
- Atlanta, GA9 studies
- Parma, OH9 studies
- Mountain View, CA8 studies
- Cleveland, OH8 studies
- Evanston, IL8 studies
- Lewisville, TX8 studies
- Lubbock, TX8 studies
- Scottsdale, AZ8 studies
- Seattle, WA8 studies
- Baltimore, MD8 studies
- Lancaster, CA8 studies
- Round Rock, TX7 studies
- Memphis, TN7 studies
- Dallas, TX7 studies
- Pittsburgh, PA7 studies
- Metairie, LA7 studies
- Charlotte, NC7 studies
- Wyoming, MI7 studies
- Anaheim, CA7 studies
- Phoenix, AZ6 studies
- Ann Arbor, MI6 studies
By state
- Alabama7 studies
- Arizona18 studies
- Arkansas4 studies
- California40 studies
- Colorado17 studies
- Connecticut10 studies
- District of Columbia3 studies
- Florida31 studies
- Georgia15 studies
- Idaho4 studies
- Illinois23 studies
- Indiana9 studies
- Iowa3 studies
- Kansas10 studies
- Kentucky13 studies
- Louisiana14 studies
- Maryland13 studies
- Massachusetts16 studies
- Michigan17 studies
- Minnesota8 studies
- Mississippi5 studies
- Missouri16 studies
- Nevada6 studies
- New Hampshire5 studies
- New Jersey6 studies
- New York30 studies
- North Carolina24 studies
- Ohio25 studies
- Oklahoma4 studies
- Oregon5 studies
- Pennsylvania13 studies
- Rhode Island10 studies
- South Carolina12 studies
- South Dakota4 studies
- Tennessee11 studies
- Texas33 studies
- Utah8 studies
- Virginia13 studies
- Washington21 studies
- Wisconsin3 studies
Recently updated studies
Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease
RecruitingObservational study
Ages 18 to 85 · All sexes · Updated Sep 28, 2026 · NCT07619547Immune Regulation in Ulcerative Colitis or Crohn s Disease
RecruitingObservational studyHealthy volunteers welcome
1 Day – 75 Years · All sexes · Updated Sep 28, 2026 · NCT00001184A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06979336A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 28, 2026 · NCT07463183Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 28, 2026 · NCT07697456A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
RecruitingPhase 3
Ages 3 and older · All sexes · Updated Sep 25, 2026 · NCT06663332A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 25, 2026 · NCT07196748Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
RecruitingPhase 2/3
Ages 2 to 17 · All sexes · Updated Sep 24, 2026 · NCT05076175Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03816345LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07186101A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
RecruitingPhase 3
Ages 2 to 19 · All sexes · Updated Sep 22, 2026 · NCT04844606A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Sep 22, 2026 · NCT07071519LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07415044A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07483073Proof of Concept Study Evaluating the Efficacy and Safety of ATH-063 Treatment in Patients With Relapsed/Refractory Moderately to Severely Active Ulcerative Colitis (UC)
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 21, 2026 · NCT07513181A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Sep 21, 2026 · NCT06095128Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Sep 16, 2026 · NCT06619990A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT06581328A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Sep 15, 2026 · NCT07185009Microbiome-targeted Diet Therapy in Ulcerative Colitis
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07520461Aquamin® for Prevention of Ulcerative Colitis J-Pouch-associate Intestinal Inflammation
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 11, 2026 · NCT07501078Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
RecruitingPhase 3
All ages · All sexes · Updated Sep 9, 2026 · NCT06651281Confirmatory Clinical Study in Active Ulcerative Colitis
RecruitingPhase 2
Ages 16 and older · All sexes · Updated Sep 9, 2026 · NCT07296315A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414 Administered Orally in Healthy Adult Participants and Patients With Active Ulcerative Colitis
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Sep 9, 2026 · NCT07749768From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.