NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities

Recruiting

Navigate Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities Among Individuals With Kidney Disease

Who can join

Ages 18 to 75 · All sexes

Full eligibility criteria

Inclusion Criteria:

* Adults ≥ 18 years of age,
* Adults who are not pregnant,
* Adults who are not incarcerated,
* Adults who have advanced kidney disease with an eGFR of 15-29 mL/min/1.73m2). No other measures are used to identify eligible patients.

Exclusion Criteria:

* Previous kidney transplant
* Previous surgery for dialysis such as an arteriovenous fistula, arteriovenous graft, or peritoneal dialysis catheter placement
* On chronic dialysis
* Conservative management or primary goal is palliation
* Incarcerated
* Pregnant\*
* Under 18 years of age
* Moderate to severe dementia
* Deaf persons
* Lacking health insurance\*\*
* Investigator Discretion: Individuals who, in the judgment of the Site PI (or designee), are deemed unsuitable for participation due to behavioral or logistical circumstances that could compromise study integrity or the safety of the participant or staff.

About the study

The overarching goal of this project is to refine and adapt previous work on the NAVIGATE-Kidney project for individuals with CKD. The investigators hypothesize that the multilevel NAVIGATE-Kidney program intervention will reduce the rate of central venous catheter use at KRT start (primary outcome), increase the rate of optimal KRT starts (secondary outcome), increase patient activation, and reduce decisional conflict (patient-centered outcomes) for individuals with advanced CKD. The project will have four (4) aims.

What is being tested

Community health worker intervention (behavioral)
Standard Care (in control arm) (behavioral)

Sponsor: University of Colorado, Denver · Participants: 448 · Started: Mar 18, 2026

Contact the study team

Lilia Cervantes, MD · Phone: 3036418009

Official record on ClinicalTrials.gov — NCT06810622

Locations in the U.S.

Colorado	Denver Health and Hospital Authority, Denver
New Mexico	University of New Mexico Health Science Center, Albuquerque (Not yet recruiting)

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.