Brain and Behavior Influences on Obesity Development From Infancy Through Childhood
Early Brain Development and Child Nutrition and Obesity
Who can join
Ages 7 to 12 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Participants from the RESONANCE cohort are eligible if the participant will reach 7-12 years of age during the proposed project period and have no food allergies. Exclusion Criteria: * Exclusion criteria for RESONANCE include: 1. In utero exposure to alcohol, cigarette, or illicit substances; 2. First trimester fetal US abnormalities; 3. Complicated pregnancy (e.g., pre-eclampsia); 4. Complicated delivery, including APGAR scores less than 8 and/or neonatal intensive care unit (NICU) admission; 5. History of neurological (e.g., epilepsy), psychiatric (e.g., anxiety or depression requiring treatment with medication) or developmental disorder (e.g., autism spectrum disorder (ASD), dyslexia); 6. Contraindications for MRI including metal in the body, claustrophobia.
About the study
The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function. This data is collected in a sub-sample of RESONANCE, a large study of families of children from infancy through childhood. The results will lay foundations for the development of early interventions to prevent or treat obesity.
What is being tested
- fMRI cue reactivity task (other)
- fMRI go no go task (other)
- Ad libitum meal test (other)
- Eating in the absence of hunger test (other)
Sponsor: Johns Hopkins University · Participants: 210 · Started: Dec 2, 2024
Contact the study team
- Susan Carnell, PhD · Phone: 410-955-7192
- Viren D'Sa, MD · Phone: 312-371-4178
Official record on ClinicalTrials.gov — NCT06861868
Locations in the U.S.
| Rhode Island | Rhode Island Hospital, Providence |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.