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BID LTM Digital Intervention in Aging
Behavioral Intervention Development Core - Long Term Memory Digital Intervention in Aging
Who can join
Ages 60 to 85 · All sexes
Full eligibility criteria
Inclusion Criteria: * Minimum of 12 years of education * English fluency: All task instructions are presented in English language text. In order to control for sufficient and equivalent participant comprehension of the procedures and instructions, we require their self-report of fluency in English. * Normal or corrected-to-normal vision * Normal or corrected-to-normal hearing * Medically healthy older adults, including those with below-average cognitive performance /MCI patients without dementia referred by neuropsychologists (i.e., no participant medical records will be reviewed). Exclusion Criteria: * Under the age of 60 * Clinical diagnosis of neurological or psychiatric disorder Clinical diagnosis of dementia or AD8 score of \>4 * Visually or hearing impaired without correction to normal * Regularly (one or more times per week) practicing an instrument within the last year * 10 years or more of formal musical instrument training
About the study
Healthy aging is typically accompanied by diminished capability for learning and retrieval of high-fidelity long-term memory (LTM). The decline in these faculties is accelerated and becomes significant deficits in LTM and cognitive control functions at the level or a diagnosis of Mild Cognitive Impairment (MCI). Training with the navigation game, relative to training with control games, is expected to improve LTM performance for older adult participants.
Researchers will compare two different digital interventions to assess whether they may be helpful in improving cognitive function.
Participants will conduct study activities remotely (e.g., at-home):
1. Baseline Assessment. Complete a series of cognitive assessments and surveys. 2. Intervention. Engage in a digital intervention for up to 8 weeks. 3. Post Intervention Assessment. Complete the same cognitive assessments and surveys as the Baseline Assessment. 4. Follow-Up Assessment. Six months after the intervention ends, participants will complete the same cognitive assessments and surveys as the Baseline Assessment.
What is being tested
- Long Term Memory (behavioral)
- Worder (behavioral)
Sponsor: University of California, San Francisco · Participants: 150 · Started: Aug 20, 2025
Contact the study team
- Melissa Arioli, AB · Phone: (415) 502-7321
Official record on ClinicalTrials.gov — NCT06916221
Locations in the U.S.
| California | University of California, San Francsico, San Francisco |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.