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Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease

Ultrasound Perfusion Estimation for Assessment of PAD

Who can join

Ages 18 to 75 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

Patient volunteers:

* Male and Female, ages 18 years old and up
* Symptom of claudication and suspected for PAD
* Scheduled for vascular testing.

Healthy volunteers:

* Male and female, ages 18-75 years old and up
* Normal BMI
* No history of smoking, cardiovascular disease, or diabetes.

Exclusion Criteria:

Patient volunteers:

* Patients with gangrene
* Patients having surgery or stent
* Patients with ulcer on their leg
* Any health condition that does not allow proper use of ultrasound scanning
* People considered in "vulnerable" populations.

Healthy volunteers:

* Include volunteers with BMI not more than 30
* No history of smoking
* No history of (diabetes, hypertension, cardiovascular diseases)
* People considered in "vulnerable" populations.

About the study

The purpose of this study is to develop a new noninvasive tool for early diagnosis of Peripheral Arterial Disease (PAD) and use the proposed method for monitoring the disease progression and the response to interventional treatment in PAD patients.

What is being tested

• Ultrasound Imaging (diagnostic test)

Sponsor: Mayo Clinic · Participants: 400 · Started: Mar 14, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06952543

Locations in the U.S.

Conditions

• Peripheral Arterial Disease

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.