Home › Opioid Overdose › NCT06954402
Resilience Among Individuals With Opioid Use Disorder
Recruiting
A Novel Human Laboratory Model of Resilience Among Individuals With Opioid Use Disorder
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: 1. Can provide informed consent and can comply with study procedures 2. Adults aged ≥18 years 3. Meet Diagnostic and Statistical Manual (DSM-5) criteria for current opioid use disorder or are currently receiving pharmacotherapy for the treatment of OUD (e.g. methadone or buprenorphine maintenance treatment \[remission\]) 4. Urine sample that tests positive for opioids 5. Test negative for pregnancy at screening (females only) Exclusion Criteria: 1. Being pregnant or breastfeeding 2. Significant mental health or physical disorder, or life circumstances, that is judged by the investigators to interfere with study participation
About the study
The goal of this clinical trial is to develop a human laboratory model of resilience in people with opioid use disorder (OUD). The investigators aim to learn if objective tasks that measure cognitive, emotional, and control aspects of resilience match up with self-reported resilience during stress and non-stress situations.
What is being tested
- Acute Stress Intervention (MAST-based) (behavioral)
- Non-Stress Intervention (NST-based) (behavioral)
Sponsor: Johns Hopkins University · Participants: 125 · Started: May 29, 2026
Contact the study team
- Suky Martinez, PhD · Phone: 410-550-0007
Official record on ClinicalTrials.gov — NCT06954402
Locations in the U.S.
| Maryland | Johns Hopkins University Bayview Medical Campus, Baltimore (Not yet recruiting) Johns Hopkins University Bayview Medical Campus, Baltimore |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.