Longitudinal Screening for Financial Hardship to Improve Outcomes in Patients With Advanced Cancer

Recruiting

Who can join

Ages 21 and older · All sexes

Full eligibility criteria

Inclusion Criteria:

1. Minimum age of 21
2. Understands English and/or Spanish
3. Has a diagnosis of advanced/metastatic cancer
4. Currently undergoing systemic therapy (enteral or parenteral) with non-curative intent
5. Has been receiving treatment for at least 2 months
6. Life expectancy of at least 6 months, in the opinion of the treating oncologist
7. Cognitively able to give informed consent

Exclusion Criteria:

1. Under the age of 21
2. Does not understand English or Spanish
3. Has cognitive deficits that would preclude understanding of consent form and/or questionnaires
4. Undergoing treatment with curative intent (e.g., adjuvant chemotherapy for breast, lung, or ovarian cancer, primary curative therapy for testis cancer or lymphoma)
5. Not undergoing systemic therapy (enteral or parenteral) with non-curative intent
6. Receiving treatment for fewer than 2 months
7. Life expectancy is less than 6 months, in the opinion of the treating oncologist

About the study

The study aims to determine whether monthly remote digital financial hardship screening among adults with advanced/metastatic cancer, undergoing outpatient systemic therapy with non-curative intent, improves patient-centered outcomes, including financial worry, health-related quality of life (HRQoL), symptom burden, patient-reported cancer treatment adherence, and exploratory outcomes of overall survival, patient-reported economic burden, patient-reported support received, patient-reported financial coping strategies, and health insurance literacy.

What is being tested

Financial Hardship Screening (other)
Enhanced Usual Care (other)

Sponsor: Alliance Foundation Trials, LLC. · Participants: 1,000 · Started: Jul 1, 2025

Contact the study team

AFT Quality Management Group Inbox · Phone: 617-732-8727

Official record on ClinicalTrials.gov — NCT06963723

Locations in the U.S.

Arizona	Dignity Health, Phoenix
New Hampshire	New Hampshire Oncology-Hematology, PA, Concord Solinsky Center for Cancer Care, Manchester
New York	New York City Health and Hospitals, New York
North Dakota	Sanford Health, Fargo
South Carolina	Gibbs Cancer Center, Spartanburg

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.