Home › Anterior Cruciate Ligament Injuries › NCT06975306

Radiographic Findings and Clinical Outcomes After Bone Grafting Patellar Defect in ACL Reconstruction

Who can join

Ages 18 to 40 · All sexes

Inclusion Criteria:

* 18-40 years old,
* male/female/gender neutral,
* all races not including vulnerable/special consideration populations,
* candidate for anterior cruciate ligament reconstruction with bone patellar bone autograft,
* compliant post operative course.

Exclusion Criteria:

* \< 18, \>41 years of age,
* prior bone patellar bone anterior cruciate ligament reconstruction,
* non-compliance post-operatively,
* nicotine dependence.

About the study

All patients will be randomly assigned using a computer randomization algorithm to one of two matched cohort groups. Patients will not be advised which group they belong to until after the completion of the study. One group will be treated with autologous bone graft for bone patellar-tendon bone (BTB) Anterior Cruciate Ligament Reconstruction (ACLR), and the other group will be treated with commercially available DBM (Demineralized bone matrix) putty. Patients will be enrolled from Banner University. Before and after surgery, patient reported outcomes including visual analog pain scale (VAS), Tegner-Lysholm and Cincinnati ACL Test. The principal investigator will evaluate the patients on subjective criteria such as pain and objective criteria including range of motion, arthritic changes seen on radiographs, infection, and ability to kneel.

What is being tested

• autologous bone grafts (procedure)
• Demineralized bone matrix (DBM) (other)

Sponsor: University of Arizona · Participants: 75 · Started: Feb 11, 2025

Contact the study team

• Marleny Munoz · Phone: 602-793-9582

Official record on ClinicalTrials.gov — NCT06975306

Locations in the U.S.

Conditions

• Anterior Cruciate Ligament Injuries

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.