Home › Epilepsy › NCT06975800
Effects of Social Feedback on Intracranial EEG
Who can join
Ages 18 to 65 · All sexes
Full eligibility criteria
Inclusion Criteria: * Patients must be between 18-65 years of age. * Patients must have a diagnosis of refractory epilepsy undergoing intracranial EEG recording for clinical purposes. * Patients with a legal guardian will be considered for participation if they are interested and, in the judgment of the research team, they are capable of performing the cognitive tasks required of the study. In those instances, the patient and their legal guardian will both participate in the informed consent process, with the legal guardian signing the consent form. Exclusion Criteria: * Patient has additional neurological condition (such as stroke or dementia) or a psychiatric condition (such as active psychosis or suicidal ideation) and are deemed inappropriate for the study. * Patients are not able to provide informed consent for any reason (e.g. encephalopathic, experiencing a seizure).
About the study
This study aims to assess the impact of social influence on direct neural recordings in human patients undergoing surgical treatment of epilepsy. 24 patients recruited from the Epilepsy Center at Dartmouth Health Medical Center (DHMC) will undergo electrode implantation throughout the brain to localize epileptogenic zones. Patients will be asked to rate their provider's warmth, competence, and other, similar traits associated with care-competency. They will then complete the picture-induced fear and math portions of the multimodal negative affect task (MNAT) during which iEEG is recorded.
What is being tested
- Low social feedback (behavioral)
- High social feedback (behavioral)
Sponsor: Trustees of Dartmouth College · Participants: 24 · Started: Apr 6, 2023
Contact the study team
- Tor D Wager, PhD · Phone: 603-646-2196
Official record on ClinicalTrials.gov — NCT06975800
Locations in the U.S.
| New Hampshire | Dartmouth Hitchcock Medical Center, Lebanon |
Conditions
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.