๐Ÿ”Ž Trials Near Me

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Epilepsy clinical trials recruiting in the U.S.

101 studies for Epilepsy are recruiting participants at sites across the United States.

Epilepsy is a brain disorder that causes people to have seizures. The seizures may be mild or severe. Learn about causes, diagnosis, and treatment.

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Recently updated studies

Evaluation and Treatment of Neurosurgical Disorders

RecruitingObservational study
Ages 4 to 99 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT00060541

Surgery as a Treatment for Medically Intractable Epilepsy

RecruitingObservational study
Ages 8 to 99 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT01273129

Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy

RecruitingPhase 1
Ages 18 to 60 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT02531880

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1

RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07563881

Modulating Movement Intention Via Cortical Stimulation

RecruitingHealthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT03233399

Investigating Epilepsy: Screening and Evaluation

RecruitingObservational study
Ages 8 to 110 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT03478852

Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database

RecruitingObservational studyHealthy volunteers welcome
Ages 8 to 120 ยท All sexes ยท Updated Sep 17, 2026 ยท NCT02107989

Diagnosing Epilepsy To EffeCT Change

Recruiting
Ages 18 to 75 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07110337

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06388707

Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

RecruitingObservational study
Ages 18 to 75 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07110454

Prospective Natural History Study of POLG Disease

RecruitingObservational study
All ages ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07775872

SeizEAR Safety Study

RecruitingHealthy volunteers welcome
Ages 18 to 70 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07088835

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures

RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Sep 2, 2026 ยท NCT07594119

Tumor Related Epilepsy

RecruitingObservational study
Ages 8 to 99 ยท All sexes ยท Updated Aug 28, 2026 ยท NCT02639325

Physiological Brain Atlas Development

RecruitingObservational study
Ages 6 to 90 ยท All sexes ยท Updated Aug 26, 2026 ยท NCT00575081

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

RecruitingPhase 2/3
Ages 18 to 75 ยท All sexes ยท Updated Aug 24, 2026 ยท NCT06132893

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

RecruitingPhase 1/2
Ages 18 to 75 ยท All sexes ยท Updated Aug 24, 2026 ยท NCT06063850

Brain Development Research Program

RecruitingObservational study
All ages ยท All sexes ยท Updated Aug 17, 2026 ยท NCT00305305

Subcortical Arousal in Perceptual Awareness

Recruiting
Ages 13 and older ยท All sexes ยท Updated Aug 10, 2026 ยท NCT06934356

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

RecruitingPhase 3
Ages 12 and older ยท All sexes ยท Updated Aug 10, 2026 ยท NCT05667142

Implementation and Cost Evaluation of Project UPLIFT

Recruiting
Ages 18 and older ยท All sexes ยท Updated Aug 7, 2026 ยท NCT06865820

Sleep Architecture & Cognition in Focal Epilepsy

Recruiting
Ages 18 to 40 ยท All sexes ยท Updated Aug 7, 2026 ยท NCT05794295

Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

RecruitingObservational study
Up to age 26 ยท All sexes ยท Updated Aug 6, 2026 ยท NCT05374824

Outcomes After Planned Discontinuation of AntiSeizure Medication

RecruitingPhase 4
Ages 18 and older ยท All sexes ยท Updated Aug 6, 2026 ยท NCT07750496

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

RecruitingPhase 3
1 Day โ€“ 18 Years ยท All sexes ยท Updated Aug 3, 2026 ยท NCT07019922

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.