Home › Knee Osteoarthritis › NCT06976138
Sleep TO Prevent Post-surgical Pain
Recruiting
Who can join
Ages 60 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * People with knee osteoarthritis, * 60 years old and older, * scheduled to have unilateral (one knee) total knee replacement surgery for osteoarthritis and * have trouble falling or staying asleep Exclusion Criteria: * currently using medications to help sleep * have completed Cognitive Behavioral Therapy for Insomnia * used either Bright Light or Negative Ion exposures in the past year * have an inflammatory rheumatologic disorder, seizure disorder * serious mental health disorder, Bipolar I disorder, substance or alcohol use disorder * serious sleep or circadian rhythm disorder, untreated sleep apnea * are pregnant or lactating * have retinal pathology * history of eye surgery (Lasik or cataract okay if more than 3 months ago) * are taking disease-modifying antirheumatic drugs * taking photosensitizing medications * are unwilling to discontinue over the counter sleep aids (for example, melatonin) for at least 2 weeks before enrolling
About the study
This research study is being done to compare different methods of addressing sleep problems before total knee replacement surgery. These methods include Cognitive Behavioral Therapy and light exposure.
What is being tested
- Cognitive-Behavioral Therapy for Insomnia (behavioral)
- Bright Light therapy via the Re-Timer® (device)
- Negative Ion exposure via IonMi Device (device)
- Sleep / Knee Osteoarthritis Education (behavioral)
Sponsor: Johns Hopkins University · Participants: 252 · Started: Jun 13, 2025
Contact the study team
- Anna Kim-Dahl · Phone: 410-550-5704
- Marise Owens · Phone: 617-732-9463
Official record on ClinicalTrials.gov — NCT06976138
Locations in the U.S.
| Maryland | Johns Hopkins School of Medicine, Baltimore |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.