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A Study of Changes to Prostate Procedures
A Randomized Controlled Trial of Modifications to Prostate Needle-Based Procedures
Who can join
Ages 18 and older · Men
Full eligibility criteria
Inclusion Criteria: Local anesthesia versus no local anesthesia during transperineal biopsy, while the patient is under IV sedation: * Patients scheduled for transperineal prostate biopsy at the JRSC or Monmouth. Standardization of a periprocedural pathway versus usual care for focal gland ablation: * Patients scheduled for a partial prostate gland ablation procedure at the JRSC. Exclusion Criteria: Local anesthesia versus no local anesthesia during transperineal biopsy, while patient is under IV sedation: * None Standardization of a periprocedural pathway versus usual care for focal gland ablation: * None
About the study
The purpose of this study is to look whether using local anesthesia during a transperineal prostate biopsy, while put to sleep by IV sedation, helps reduce the number of people who feel significant pain in the recovery room. The researchers will also look at how local anesthesia affects the amount of pain medication used, how quickly people can go home after the biopsy, and how well they recover after leaving the hospital.
What is being tested
- Prostate Biopsy (procedure)
- Local anesthesia (drug)
Sponsor: Memorial Sloan Kettering Cancer Center · Participants: 800 · Started: May 19, 2025
Contact the study team
- Jonathan Fainberg, MD, MPH · Phone: 646-422-4894
- Behrar Ehdaie, MD, MPH · Phone: 646-422-4406
Official record on ClinicalTrials.gov — NCT06986083
Locations in the U.S.
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.