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Transcutaneous Electrical Nerve Stimulation for Pain Mitigation During Intrauterine Device Placement

Recruiting

A Randomized Controlled Trial of Transcutaneous Electrical Nerve Stimulation for Pain Mitigation During Intrauterine Device Placement

Who can join

Ages 18 and older · Women

Full eligibility criteria
Inclusion Criteria:

* Provision of signed and dated informed consent form for IUD Insertion
* Stated willingness to comply with all study procedures
* English speaking individuals aged 18 years or older
* Presenting for IUD initiation during ambulatory care visit at MUSC Women's Health
* Opting for either LNG 52mg or copper T380A IUD

Exclusion Criteria:

* Contraindication to IUD initiation (i.e. pregnancy, current pelvic infection, distorted uterine anatomy)
* Contraindication or allergy to ibuprofen
* History of a chronic pain disorder
* Recent opioid use in the previous 30 days
* History of a cardiac arrhythmia
* History of heart disease (i.e. atrial fibrillation, congestive heart failure)
* Presence of an implantable device with an electrical discharge (i.e. pacemaker)
* BMI \> 50 (class IV obesity)
* History of TENS use
* Planned pain intervention outside standard of care (i.e. paracervical block, misoprotol) OR preprocedure use of non-standard pain medication (i.e. benzodiazepines, marijuana, muscle relaxers, gabapentin, benadryl)
* History of epilepsy

About the study

Investigators are conducting a study to determine whether high frequency transcutaneous electrical nerve stimulation (hfTENS) is effective at reducing pain in women having an IUD inserted.

What is being tested

Sponsor: Medical University of South Carolina · Participants: 86 · Started: Dec 1, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06991075

Locations in the U.S.

South CarolinaMUSC Women's Health- Cannon Street, Charleston

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.