Home › Parkinson's Disease › NCT06994728

Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait

Characterization of Subthalamic Nucleus Deep Brain Stimulation Laterality on Visuospatial Attention and Correlation to Freezing of Gait in Parkinson's Disease

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Subjects above 18 years of age
* Subjects with freezing of gait
* Subjects with bilateral STN-DBS surgery as part of their clinical care for Parkinson's disease

Exclusion Criteria:

* Uncorrected visual or hearing impairments, as indicated by self-report
* Individuals who are pregnant or expect to become pregnant during the course of the study
* Individuals with dementia or relevant brain lesions impacting cognition or gait

About the study

The purpose of this research is to determine how deep brain stimulation (DBS) for Parkinson's disease affects attention and visuospatial function. Additionally, this study will evaluate how deficits in visual attention are associated with freezing of gait (FOG) in Parkinson's disease. There is currently no reliable treatment for FOG and little is understood about the underlying reason this occurs. Some recent research has found that stimulating the right side of the brain seems to improve FOG. The right side of the brain is also paramount for visual attention, which is why investigators are conducting this study.

What is being tested

• Left STN-DBS on, right STN-DBS off first (device)
• Right STN-DBS on, left STN-DBS off first (device)

Sponsor: Medical University of South Carolina · Participants: 12 · Started: Apr 1, 2025

Contact the study team

• Nathan DeTurk, MD · Phone: 843-792-3221

Official record on ClinicalTrials.gov — NCT06994728

Locations in the U.S.

Conditions

• Parkinson's Disease
• Walking Problems

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.