Home › Low Back Pain › NCT07003113

Ischemic Preconditioning in Osteoarthritis and Back Pain

Who can join

Ages 50 and older · All sexes

Inclusion Criteria:

* Reported Knee Pain using ACR Criteria
* Reported Back Pain using ODI Criteria \> 12
* Ability to walk for at least 3 minutes without the use of aids
* Ability to provide written informed consent

Exclusion Criteria:

* Younger than 50 years old
* History of Knee or Hip Replacements
* History of steroid injection within the previous 6 months
* Presence of neuromuscular joint condition that affects lower extremity function
* History of blood clots in the leg or any condition in which compression of the thigh is contraindicated
* History of heart failure or thrombosis
* Allergic to ultrasound gel
* History of spine surgery
* Non-English speaker
* Currently pregnant or intends to become pregnant during the study

About the study

We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.

What is being tested

• Ischemic Preconditioning (device)
• Sham Intervention (device)

Sponsor: University of Illinois at Chicago · Participants: 24 · Started: Sep 12, 2025

Contact the study team

• Shraddha Sudhir · Phone: 312-413-5118

Official record on ClinicalTrials.gov — NCT07003113

Locations in the U.S.

Conditions

• Low Back Pain
• Knee Osteoarthritis
• Back Pain

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.