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Enhancing Smoking Cessation for African American People Everywhere

RecruitingPhase 2

A National Test of a Culturally Tailored Smartphone-based Smoking Cessation and Mental Health Intervention for Black Adults With HIV

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* At least 18 years of age
* Identify as Black/African American
* Living with HIV
* Biochemical verification of self-reported smoking status following minimum study specified smoking rate endorsement
* Motivated to quit smoking
* Must be ready to quit cigarettes within 14 days of full enrollment
* Moderate or higher anxiety sensitivity OR elevated anxiety OR depression
* Must be willing to download a mobile app onto their personal phone
* Must be willing to use NRT
* Possess an Android/Apple smartphone that is compatible with the mobile app
* Demonstrate 7th grade level proficiency in English (≥4 on the Rapid Estimate of Adult Literacy in Medicine-Short Form \[REALM-SF\])
* Valid proof of identification (photo of valid US ID)

Exclusion Criteria:

* Legal situations which may interfere with study participation
* Not being fluent in English
* High blood pressure that is not under control
* Having experienced a heart attack within the past 2 weeks
* Pregnant of planning to become pregnant within the next six months

About the study

The present study aims to investigate the efficacy of an mHealth smoking cessation and HIV disease management intervention among a nationally representative sample of African America/Black (hereafter refer to as Black) persons with HIV/AIDS (PWH) who smoke cigarettes. Participants will be randomized into one of three conditions: (1) the intervention, ESCAPE (Enhancing Smoking Cessation for African American People Everywhere) + Nicotine Replacement Medications (NRT), (2) the National Cancer Institute's (NCI) quitSTART app, the standard mobile smoking cessation treatment + NRT, and (3) an assessment-only control group + NRT.

What is being tested

Sponsor: University of Houston · Participants: 300 · Started: Jun 30, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07024992

Locations in the U.S.

OklahomaUniversity of Oklahoma Health Sciences Center, Oklahoma City

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.