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Shaping Habitual Impulses For a Tobacco-free Style
Approach Bias Retraining to Augment Long-Term Smoking Cessation Among a Diverse Sample
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * At least 18 years of age * Ability to speak English fluently * Ability to read English fluently * Ability to write in English fluently * Biochemical verification of self-reported smoking status following minimum study specified smoking rate endorsement * Motivated to quit smoking * Willing to attend in-person visits * Provide written informed consent, accepting study inclusion criteria and the randomized group assignment * English literacy of 7th grade or higher, as indicated by a score of 4 or greater on the Rapid Estimate of Adult Literacy in Medicine-Short Form (REALM-SF) Exclusion Criteria: * Having used an e-cigarette in the past 3 months * Having initiated any mental health therapy or pharmacotherapy within the past 3 months * Being currently in therapy for substance abuse (including nicotine dependence) * Being currently enrolled in any other studies at the RESTORE lab to help quit smoking * Currently using any NRT or psychotherapy products for nicotine cessation * Currently using Bupropion as a smoking cessation aid and antidepressant * Currently pregnant or planning to become pregnant * Having high blood pressure that is not under control * Having a heart attack within the past 2 weeks * Having Visual impairments * Hand-motoric impairments * Currently suicidal or high suicide risk or current or past psychotic disorders of any type, bipolar disorder, schizophrenia or schizoaffective disorder, anorexia, bulimia assessed using the Mini Neuropsychiatric Interview * Cognitive impairment, verified via a score of ≥8 on the Six-Item Cognitive Impairment Test (6-CIT)
About the study
The present investigation aims to assess the efficacy of an innovative and novel smoking cessation intervention that integrates approach bias retraining (ABR) and standard smoking cessation treatment (ST). Participants will be randomized to either: (1) standard smoking cessation treatment and approach bias retraining (ST+ABR); (2) ST+Sham; or (3) ST-only.
What is being tested
- ST+ABR (behavioral)
- ST+Sham (behavioral)
- ST Only (behavioral)
Sponsor: University of Houston · Participants: 300 · Started: Mar 24, 2026
Contact the study team
- Lorra Garey, PhD · Phone: 713-743-8056
- Ashley Ruiz, B.S. · Phone: 713-743-8056
Official record on ClinicalTrials.gov — NCT07025772
Locations in the U.S.
| Texas | RESTORE Laboratory: Research on Emotion, Substance Use Treatment Outcomes, Rehabilitation, and Empowerment, Houston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.