Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method
Recruiting
Mindful Self-Compassion for Anxiety and Depression: A Randomized Comparison of In-Person Versus Videoconference Delivery
Who can join
Ages 18 to 65 · All sexes
Full eligibility criteria
Inclusion Criteria: * Must have a primary anxiety disorder (social anxiety disorder, generalized anxiety disorder, panic disorder, or agoraphobia) or major depressive disorder, current * Must score low on self-compassion, as measured by the self-compassion scale * Must understand study procedure and willing to participate in all testing visits, and treatment as assigned * Must be able to give informed consent to the study procedures Exclusion Criteria: * Comorbid psychiatric disorder other than anxiety or depression, such as psychotic disorder, obsessive compulsive disorder, eating disorders (i.e., anorexia and bulimia), bipolar disorder; developmental or organic mental disorders; and current (past 6 months) substance use disorders and current post-traumatic stress disorder as assessed by clinician at screening visit * A serious medical condition that may result in surgery or hospitalization. * A history of head trauma causing prolonged loss of consciousness, or ongoing cognitive impairment * Inability to understand study procedures or informed consent process, or significant personality dysfunction likely to interfere with study participation (assessed during the clinical interview). * Subjects who will be non-compliant with the study procedures. This may include planned travel out of town. * Subjects taking some psychiatric medication such as barbiturates or antipsychotics. Sleep medications and some anti-depressants will be allowed, if the subject has been taken at stable dose 8 weeks prior to baseline and the patient plans to continue at the same dose through the trial. * Concurrent psychotherapy initiated within 1 month of screen interview, or ongoing psychotherapy of any duration directed specifically toward the treatment of anxiety (such as Cognitive Behavioral Therapy). * Individuals who have completed a course of MSC or an equivalent meditation training in the last year. * Individuals reporting significant active suicidal ideation or suicidal behaviors within the past year. * Individuals with a medical condition (i.e., epilepsy) that may be exacerbated by study treatment, as determined by a study physician or nurse practitioner based on history, physical, and/or labs. * Adults unable to consent * Pregnant women * Prisoners
About the study
The study will compare the delivery of an 8-week Mindful Self-Compassion training, in-person against video-conference, on anxiety and depression symptom severity in patients with diagnosed anxiety disorders (generalized anxiety disorder, social anxiety disorder, and panic disorder) or major depressive disorder or dysthymia.
What is being tested
- Mindful Self-Compassion (behavioral)
Sponsor: Georgetown University · Participants: 80 · Started: Jun 1, 2025
Contact the study team
- Charisma Study Coordinator · Phone: 202-687-7283
- Thirein Study Coordinator · Phone: 202-687-7283
Official record on ClinicalTrials.gov — NCT07028216
Locations in the U.S.
| District of Columbia | Georgetown University Medical Center, Washington D.C. |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.