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PENG vs Femoral Block for Hip Fracture Analgesia

PENG vs Femoral Block for Hip Fracture, A Pragmatic Cluster-Randomized Study

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

1. Male or female ≥ 18 years of age.
2. ASA Classification 1-4
3. Documentation of a hip fracture diagnosis along with radiologic read indicating fracture location
4. Written, informed consent for analgesic peripheral block placement

Exclusion Criteria:

1. Altered mental status to the extent that it limits ability to report pain score
2. Patient or health care proxy refusal of analgesic nerve block
3. Allergy to study medications or contraindication to peripheral nerve block
4. Peri-prosthetic fracture
5. Any additional fractures in a patient with a unilateral hip fracture

About the study

This study aims to compare the Pericapsular Nerve Group (PENG) block with femoral block for hip fracture pain. Participants presenting to the hospital with a diagnosis of hip fracture and consenting to analgesic block will receive either a PENG or femoral block. The choice of block will be dictated by a randomized monthly schedule, and all participants presenting during each four-week period will receive the designated block. A sub-group analysis will be performed to determine any difference in efficacy in participants with intracapsular versus extracapsular fractures.

What is being tested

• PENG Block Administration (procedure)
• Femoral Block Administration (procedure)
• Bupivacaine , epinephrine Dexamethasone (drug)

Sponsor: Weill Medical College of Cornell University · Participants: 352 · Started: Jul 10, 2025

Contact the study team

• Michele Steinkamp, BSN, RN · Phone: 212-746-2953
• Mark Abdelmassih, B.S. · Phone: 212-746-2774

Official record on ClinicalTrials.gov — NCT07073209

Locations in the U.S.

Conditions

• Hip Injuries and Disorders
• Pain

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.