Vascular Trial Associated Registry Pilot

Inclusion Criteria:

* Age greater than or equal to 45 at time of enrollment
* Patient is scheduled for a PVI or has recently had a PVI in the last 30 days
* Patient data is being submitted to Fivos, who is acting as the data collection subcontractor for the VQI-PVI registry.
* Atherosclerotic vascular disease

Exclusion Criteria:

* Patients who cannot consent for themselves
* Allergy to Clopidogrel
* Patients unable to stop clopidogrel for other medical reasons
* Patients on dual pathway inhibition (DPI) with low dose rivaroxaban (2.5mg twice a day) that are unable to stop these medications
* Allergy to aspirin
* Nonatherosclerotic vascular disease
* Patients undergoing open bypass at the same time as the peripheral transcutaneous angioplasty
* Patients with high bleeding risk (HBR) defined as:

  * History of major bleeding, active bleeding disorder, severe renal impairment (CrCl \<30), concurrent anticoagulation, platelet count \<100,000
  * Recent stroke (within 6 months)
  * Current warfarin therapy or full dose therapeutic direct oral anticoagulants (DOAC).
* Patients unwilling or unable to comply with standard of care follow-up visits
* Pregnant women
* Prisoners