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NYU Epilepsy Self-Management Study
Recruiting
Economic Evaluation of Managing Epilepsy Well (MEW) Network Epilepsy Self-Management Programs
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Adults (≥18 years) * English-speaking (UPLIFT and PACES) or Spanish-speaking (UPLIFT only). * Diagnosed with epilepsy for at least one year * Able to understand the informed consent and provide consent * Elevated depressive symptoms - Patient Health Questionnaire-9 (PHQ-9) score ≥10; applies to UPLIFT only Exclusion Criteria: * Severe depressive symptoms (score of ≥20 on PHQ-9) * Active suicidal ideation (score of ≥1 on PHQ-9 item #9 or otherwise reported during screening) * Active psychotic disorder (psychiatric diagnosis and/or antipsychotic medications in the electronic health records (EHR) * Significant cognitive impairment (indicated in the EHR or evident during screening)
About the study
The investigators will conduct two-arm randomized controlled trials (RCTs) comparing effects of UPLIFT vs. enhanced usual care and PACES vs. enhanced usual care, respectively, on quality of life, depressive symptoms and seizures over 12 months in NYU patients with epilepsy.
What is being tested
- UPLIFT (behavioral)
- PACES (behavioral)
- Enhanced Usual Care (behavioral)
Sponsor: NYU Langone Health · Participants: 108 · Started: Sep 16, 2025
Contact the study team
- Tanya Spruill, PhD · Phone: 646-501-3429
Official record on ClinicalTrials.gov — NCT07087821
Locations in the U.S.
| New York | NYU Langone Health - NYU Langone Hospital-Brooklyn, Brooklyn NYU Langone Health - NYU Comprehensive Epilepsy Center, New York |
Conditions
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.