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Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

RecruitingHealthy volunteers welcome

Impact of Nd: YAG Laser Photobiostimulation on Healing of Gingiva Following Tooth Extraction and Alveolar Ridge Preservation

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Participants who are ≥ 18 years old,
* Patients who are scheduled for the treatment of tooth extraction and alveolar ridge preservation (ARP)
* No contraindications for tooth extraction and alveolar ridge preservation based on electronic health records.
* Participants who can express the level of pain
* Participants who self-report "not pregnant"

Exclusion Criteria:

* Untreated periodontal disease
* Acute infection of the teeth
* Use of antibiotics within the last three months.
* Pregnant or lactating women
* Use of bisphosphonates based on EHR
* Alveolar bone defects occurred or were detected during tooth extraction

About the study

The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation. Investigators plan to assess the impact of laser treatment on wound healing by measuring salivary biomarkers, gingival wound size and surveying for the use of pain reduction and patient satisfaction. The intervention group will receive extraction and alveolar ridge preservation with Nd-YAG laser photobiostimulation on days 1, 3, and 7 following extraction and socket preservation, while the control group will receive the standard of care extraction and alveolar ridge preservation without the laser

What is being tested

Sponsor: Medical University of South Carolina · Participants: 39 · Started: Nov 5, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07095556

Locations in the U.S.

South CarolinaMUSC College of Dental Medicine, Graduate Periodontics Clinic, Charleston

Conditions

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.