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Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System

RecruitingHealthy volunteers welcome

Who can join

Ages 40 to 75 · Men · Healthy volunteers welcome

Full eligibility criteria
Eligibility Criteria:

* Receive care within the BJC Health System
* Have had at least one primary care physician appointment in the calendar year of PSA screening (primary care)
* Be male
* Not have a history of prostate cancer
* Meet one of the following risk criteria:

  * High Risk for Prostate Cancer

    * African American, between the ages of 40 and 75 (inclusive), or
    * Family history of prostate, breast, ovarian, and/or pancreatic cancer, or
    * Known familial germline mutation OR
  * Average Risk for Prostate Cancer

    * Between the ages of 50 and 75 (inclusive)

About the study

\- The investigators propose a clinical trial to evaluate the impact of annual shared decision making for PSA screening, supported by system-level enhancements to promote evidence-based care:

* Defined referral thresholds within the health maintenance reminder, aligned with clinical risk stratification per NCCN guidelines. * Enhanced clinical decision support (CDS) tools to reduce provider variation and ensure guideline-concordant screening and referral practices. * The goal is to reduce late-stage presentation without increasing overdiagnosis-ensuring that prostate cancer screening is both accessible and clinically effective.

What is being tested

Sponsor: Washington University School of Medicine · Participants: 40,000 · Started: Aug 11, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07109427

Locations in the U.S.

MissouriWashington University School of Medicine, St Louis

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.