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Vaped Phenanthrene
Investigating Vaped Phenanthrene Biomarkers in Former Smokers
Who can join
Ages 21 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * \> 21 years of age * In good physical \& mental health * In stable physical \& mental health * Have tried vaping * Former daily cigarette smokers who quit 1-20 year ago * Non-smokers who have not used tobacco or nicotine products Exclusion Criteria: * Has any respiratory disease (ex - asthma, COPD, etc...) * Has/had high blood pressure * Has/had liver disease * Has/had cancer * Has experience negative effects when vaped previously * Pregnant or nursing
About the study
Some people who used to smoke cigarettes continue to be at higher risk of developing lung cancer, even years after quitting. This study will look to see if a specific chemical, phenanthrene, is broken down in the lungs of former smokers through more harmful pathways than never-smokers. If former smokers break down chemicals that enter their lungs through more harmful pathways this might be putting them at higher risk for developing lung cancer even though they quit smoking. This information may help find better ways to prevent or treat cancer in the future.
This study is under an IND, but the drug is not being studied; instead, it is being used as a marker for drug metabolism.
What is being tested
- D10-phenanthrene (other)
Sponsor: University of Minnesota · Participants: 100 · Started: Sep 1, 2026
Contact the study team
- Aleksandra Alcheva · Phone: 612-422-8902
Official record on ClinicalTrials.gov — NCT07134426
Locations in the U.S.
| Minnesota | University of Minnesota, Minneapolis |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.