Post-stroke Pain tAN-fMRI
Investigating the Feasibility, Efficacy, and Renormalization of Pain-Regulation Brain Circuits Underlying At-Home Transcutaneous Auricular Neuromodulation (tAN) for Managing Chronic Post-Stroke Pain
Who can join
Ages 18 to 80 · All sexes
Full eligibility criteria
Inclusion Criteria: * Age 18-80 * Have the capacity and ability to provide one's own consent in English and sign the informed consent document. * Ischemic or hemorrhagic stroke that occurred at least 6 months prior Exclusion Criteria: * Primary intracerebral hematoma or subarachnoid hemorrhage * Documented history of dementia * Documented history of uncontrolled depression or psychiatric disorder * Uncontrolled hypertension despite treatment, specifically SBP (Systolic Blood Pressure) / DBP (Diastolic Blood Pressure) \>=180/100mmHg * Contraindicated for MRI scanning * Pregnancy
About the study
The purpose of this study is to explore whether 4 weeks of at-home transcutaneous auricular neurostimulation (tAN) can reduce chronic pain after a stroke. Investigators will recruit up to 24 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.
What is being tested
- Transcutaneous Auricular Neurostimulation (device)
Sponsor: Medical University of South Carolina · Participants: 24 · Started: Jan 8, 2026
Contact the study team
- Institutional RBFHR Recruitment Contact · Phone: 843-792-9502
Official record on ClinicalTrials.gov — NCT07144436
Locations in the U.S.
| South Carolina | 30 Bee Street, Charleston Medical University of South Carolia, Charleston (Not yet recruiting) |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.