Home › Opioid Overdose › NCT07158853
Combined tDCS and Cognitive Training as an Adjunctive Treatment in Opioid Use Disorder
RecruitingPhase 1
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Ability to provide consent and comply with study procedures * Diagnostic and Statistical Manual of Mental Disorders criteria for OUD * Undergoing medication treatment for OUD. Participants may have current comorbid drug use, but primary diagnosis must be OUD * Intention to remain in the study until intervention completion. Exclusion Criteria: * Any medical condition with neurological sequelae * Head injury resulting in skull fracture or loss of consciousness of \>30 minutes * Any tDCS or MRI contraindication (tDCS: history of seizures, metallic cranial plates/screws or implanted device, history of eczema on scalp. MRI: unapproved metallic implants, pacemakers or any other implanted electrical device, shrapnel, metallic braces, non-removable body piercings, pregnancy, breathing or movement disorder, or claustrophobia) * Any psychotic disorder (participants with other treated and stable psychiatric disorders will be included) * Presence of a condition that would render study measures impossible to administer or interpret * Age younger than 18 * Primary current substance use disorder on a substance other than opioids except for caffeine or nicotine * In treatment instead of jail * Pregnancy * Disrespectful behavior towards the investigators and staff.
About the study
The overall goal of this study is to investigate the added benefit of a neuromodulation intervention in individuals taking medication for treatment for Opioid Use Disorder(OUD).
What is being tested
- Transcranial Direct Current Stimulation (tDCS) (device)
Sponsor: University of Minnesota · Participants: 40 · Started: Feb 4, 2026
Contact the study team
- Calvin Cahill · Phone: 952-444-0137
Official record on ClinicalTrials.gov — NCT07158853
Locations in the U.S.
| Minnesota | University of Minnesota, Minneapolis |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.