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Supporting Treatment Resilience With Optimized Nutrition and Guided Exercise in Head and Neck Cancer Patients Undergoing Chemoradiation

Recruiting

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Adults ≥18 years old with biopsy-confirmed squamous cell carcinoma of the head and neck
* Planned for definitive or adjuvant chemoRT
* ECOG performance status 0-2
* Ability to participate in light-to-moderate physical activity
* Able to provide informed consent

Exclusion Criteria:

* Severe malnutrition requiring exclusive enteral feeding at baseline
* Comorbidities that preclude safe participation in exercise
* Cognitive or psychiatric conditions that impair study engagement

About the study

The purpose of this study to find out whether a structured lifestyle intervention-combining nutrition counseling, guided exercise, and wellness education-can help reduce treatment-related side effects and improve physical function, resilience, and quality of life in patients with head and neck cancer undergoing chemoradiation therapy (chemoRT).

Benefits of research cannot be guaranteed but we hope to learn whether this intervention is feasible and acceptable during active cancer treatment, and whether it can help preserve lean body mass, improve strength and endurance, and support emotional well-being. The findings will inform the design of a future larger clinical trial.

What is being tested

Sponsor: Renown Health · Participants: 30 · Started: Sep 15, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07160296

Locations in the U.S.

NevadaConrad Breast Center at South Meadows, Reno
Renown Regional Medical Center, Reno

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.