Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing
Recruiting
Who can join
Ages 21 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Provide informed consent Be at least 21 years of age or older Provide a breath sample for measuring carbon monoxide (CO ≥ 8 ppm) Stable tobacco use patterns for at least two months Exclusion Criteria: For exclusive cigarette smokers: Smoke at least 10 cigarettes daily and do not use NVPs regularly (no more than 9 times in the last month). For dual cigarette/NVP users: Smoke at least 10 cigarettes daily and use NVPs at least 3 times in a week (report use of closed nicotine salt system) For both groups: Have plans to move out of the area Have a serious or unstable physical or mental health condition Taking a tobacco cessation medication or medication that interferes with nicotine metabolism, motivation or reinforcement Report concrete, immediate plans to alter/quit using their usual nicotine products at the beginning of the study Being pregnant or lactating
About the study
This study will investigate the effects of a very-low-nicotine cigarette (VLNC) standard, e-cigarette price, and illegal cigarette price on illegal product purchasing and alternative product use in a virtual marketplace.
What is being tested
- Nicotine Content (behavioral)
- Illegal cigarette price (behavioral)
- E-cigarette price (behavioral)
Sponsor: Virginia Polytechnic Institute and State University · Participants: 70 · Started: Dec 1, 2025
Contact the study team
- Kirstin Gatchalian · Phone: 540-526-2071
- Madeleine Mason, PhD · Phone: 540-526-2114
Official record on ClinicalTrials.gov — NCT07161050
Locations in the U.S.
| Virginia | Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.