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Improving Speech in Noise Using Noninvasive Stimulation
RecruitingHealthy volunteers welcome
Noninvasive Vagus Nerve Stimulation for Improved Speech in Noise Perception
Who can join
Ages 25 to 55 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * 25-55 years old * Proficiency in English * TBI group: history of traumatic brain injury by blast or physical trauma * Normal hearing group: no history of traumatic brain injury Exclusion Criteria: * Other neurological diseases or related conditions will be excluded (e.g., large vessel stroke, seizures). We will exclude patients with severe medical diseases that may be associated with impaired cognition (e.g., heart failure, dialysis dependent kidney disease, brain cancer). Further, psychiatric diseases that are unlikely to be related to trauma will be excluded (e.g., schizophrenia). Patients with histories of severe psychiatric disease prior to trauma exposure will be excluded. * Current illicit or prescription drug abuse (within the last two months) * Any taVNS contraindication, including but not limited to the presence of unremovable metal in the left ear, known heart conditions, medications that influence neurotransmitters thought to be critical for vagus nerve stimulation (norepinephrine, acetylcholine, and serotonin), or implanted medical devices such as a pacemaker.
About the study
Traumatic brain injury, a common injury in military service personnel, often leads to poor processing of speech in noisy environments. The goal of the current study is to better understand the brain basis for this difficulty and evaluate a new approach to improving speech in noise perception.
What is being tested
- Cymba Conchae stimulation (device)
- Earlobe stimulation (device)
Sponsor: University of Florida · Participants: 55 · Started: Mar 21, 2026
Contact the study team
Official record on ClinicalTrials.gov — NCT07176936
Locations in the U.S.
| Florida | UF Health at the University of Florida, Gainesville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.