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Predictive Value of Lung Ultrasound for Respiratory Decompensation in Late Preterm Neonates

Who can join

34 Weeks – 36 Weeks · All sexes

Inclusion Criteria:

* Inborn infants born between 34w0d and 36w6d gestational age
* In RA or 1 Litre per minute 1LPM NC (room air (RA) or nasal cannula (NC))
* Admitted to NICU or Well Baby Nursery (WBN)

Exclusion Criteria:

* Patients born \<34 weeks or \>36w6d
* Major genetic anomaly or syndromic condition
* Cardiac or pulmonary structural defects
* Cord pH \<7.0 or 5 minute APGAR 5 or less
* Suspected fetal hemorrhage or other source of significant anemia at birth

About the study

Respiratory morbidity presents a significant clinical challenge in the neonatal period, and an individual patient's clinical course is often difficult to predict. This is especially true for late-preterm infants, who share some of the same risks of premature babies in terms or respiratory morbidity, but whose births may not always be attended by a neonatologist, or who may be born at hospitals with lower level Neonatal Intensive Care Units (NICUs) and require transfer if they decompensate.

With this study, the aim is to 1) determine the efficacy of early point of care lung ultrasound (LUS) to predict respiratory decompensation in the first 48 hours of life in late preterm infants and 2) to compare the performance of three lung ultrasound scoring systems, 3 type-of-lung, high risk pattern and total LUS scoring systems.

What is being tested

• Point of care lung ultrasound (diagnostic test)

Sponsor: Hackensack Meridian Health · Participants: 300 · Started: Nov 6, 2025

Contact the study team

• Jeanette Haugh · Phone: 551-996- 3457

Official record on ClinicalTrials.gov — NCT07216053

Locations in the U.S.

Conditions

• Premature Birth
• Collapsed Lung
• Breathing Problems

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.