Home › Hyperglycemia › NCT07218133

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Long-segment spinal fusions (defined as constructs spanning at least L2-pelvis for thoracolumbar fusions or C2-T2 for cervical fusions)
* Ability to undergo a reliable neurologic examination and pain assessments

Exclusion Criteria:

* Patients \<18 years of age
* Shorter-segment spinal fusions than those described above
* Undergoing current active cancer therapy
* Undergoing treatment with immunosuppressive drugs
* Additional spinal surgery within past 6 months
* Sustained bradycardia or presence of pacemaker
* History of substance abuse

About the study

This study is a randomized controlled trial that will evaluate the effect of non-invasive auricular vagal nerve stimulation on inflammatory markers, glycemic control, postoperative pain, and inflammation-related clinical outcomes after long-segment spinal fusion surgeries when compared to current accepted management.

What is being tested

• Auricular vagus nerve stimulation (device)
• Sham Auricular Vagus nerve Stimulation (device)

Sponsor: Alexander T. Yahanda · Participants: 50 · Started: Oct 8, 2025

Contact the study team

• Alexander T Yahanda, MD, MPHS · Phone: 3143690198

Official record on ClinicalTrials.gov — NCT07218133

Locations in the U.S.

Conditions

• Hyperglycemia
• Neurologic Diseases
• Pain After Surgery
• After Surgery

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.