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Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

Recruiting

A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial of the Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

Who can join

Ages 45 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Open angle, pseudoexfoliative or pigmentary glaucoma
* IOP at preoperative visit of ≥ 20mmHg and ≤ 40mmHg
* Visual field mean deviation score of -3dB or worse
* Area of healthy, free and mobile conjunctiva in the target quadrant
* Shaffer angle grade ≥ 2 in the target quadrant

Exclusion Criteria:

* Angle closure glaucoma
* Congenital, neovascular or other secondary glaucomas
* Previous intraocular surgery, with the exception of uncomplicated cataract surgery
* Previous glaucoma shunt/valve in the target quadrant
* Clinically significant inflammation or infection in the study eye within 30 days prior to the operative visit
* History of corneal surgery, corneal opacities or corneal disease
* Retinal or optic nerve disorders, either degenerative or evolutive, that are not associated with the existing glaucoma condition

About the study

A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial

What is being tested

Sponsor: Avisi Technologies Inc. · Participants: 165 · Started: Nov 7, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07220876

Locations in the U.S.

ArizonaArizona Advanced Eye Research, Glendale
CaliforniaSacramento Eye Consultants, Sacramento
ColoradoICON Eye Care, Grand Junction
OhioCleveland Clinic- Cole Eye Institute, Cleveland (Not yet recruiting)
PennsylvaniaScheie Eye Institute, Philadelphia (Not yet recruiting)
Wills Eye Hospital, Philadelphia (Not yet recruiting)
TexasGlaucoma Associates of Texas, Dallas
University of Texas Southwestern, Dallas (Not yet recruiting)
WisconsinThe Eye Centers of Racine & Kenosha, Kenosha

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.