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Open-Angle Glaucoma clinical trials recruiting in the U.S.

33 studies for Open-Angle Glaucoma are recruiting participants at sites across the United States.

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Recently updated studies

REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular Hypertension

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07675824

A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular Hypertension

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07661329

Hydrus® Microstent New Enrollment Post-Approval Study

Recruiting
Ages 45 and older · All sexes · Updated Sep 22, 2026 · NCT04553523

Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07075718

iDose TR Administration in an Office-Based Surgery Setting

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07816692

A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases

RecruitingObservational studyHealthy volunteers welcome
Ages 20 to 79 · All sexes · Updated Aug 25, 2026 · NCT07780890

Caffeine Consumption in Glaucoma Patients and Healthy Subjects

RecruitingHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Aug 20, 2026 · NCT03675412

Travoprost Intraocular Implant + iStent Infinite

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06066645

Adaptive Optics Retinal Imaging

RecruitingHealthy volunteers welcome
Ages 21 and older · All sexes · Updated May 8, 2026 · NCT05370287

Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

Recruiting
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07408154

24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients

RecruitingPhase 4
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT07325240

DSLT for Reducing Medication in Glaucoma

RecruitingObservational study
All ages · All sexes · Updated Apr 20, 2026 · NCT07390890

Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT07495852

A Trial of Hydrus Microstent Versus Goniotomy

Recruiting
Ages 40 to 85 · All sexes · Updated Mar 30, 2026 · NCT06289491

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT07217678

Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg

RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT07400926

Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone

RecruitingPhase 4
Ages 45 and older · All sexes · Updated Jan 21, 2026 · NCT06848946

Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

Recruiting
Ages 45 and older · All sexes · Updated Dec 15, 2025 · NCT07220876

Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Nov 14, 2025 · NCT07228221

Electrical Stimulation for Vision Neuroenhancement in Glaucoma

Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2025 · NCT06685211

Diagnostic Innovations in Glaucoma Study

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 24, 2025 · NCT00221897

Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Sep 12, 2025 · NCT04396002

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.