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Open-Angle Glaucoma clinical trials recruiting in the U.S.
32 studies for Open-Angle Glaucoma are recruiting participants at sites across the United States.
Cities with the most studies
- Kenosha, WI5 studies
- Houston, TX4 studies
- Santa Rosa, CA4 studies
- Philadelphia, PA4 studies
- El Paso, TX3 studies
- Oklahoma City, OK3 studies
- Boston, MA3 studies
- Austin, TX3 studies
- Roswell, GA3 studies
- Newport Beach, CA3 studies
- New York City, NY3 studies
- Dallas, TX3 studies
By state
- Arizona4 studies
- California9 studies
- Colorado3 studies
- Florida6 studies
- Georgia3 studies
- Maryland3 studies
- Massachusetts4 studies
- Minnesota3 studies
- New York3 studies
- Oklahoma3 studies
- Pennsylvania5 studies
- Texas9 studies
- Wisconsin5 studies
Recently updated studies
Hydrus® Microstent New Enrollment Post-Approval Study
Recruiting
Ages 45 and older · All sexes · Updated Nov 12, 2026 · NCT04553523A Phase 2a Study Comparing the Efficacy, Safety and Tolerability of Pregabalin Eye Drops Comparing With Timolol Eye Drops in Adults With Glaucoma or High Eye Pressure.
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07913074Adaptive Optics OCT Evaluation of Rhopressa's Effects on the Retinal Ganglion Cells in Glaucoma Patients
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07847073Electrical Stimulation for Vision Neuroenhancement in Glaucoma
Recruiting
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT06685211A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma
RecruitingPhase 3
Ages 45 and older · All sexes · Updated Oct 9, 2026 · NCT06822738Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma
Recruiting
Ages 45 and older · All sexes · Updated Oct 7, 2026 · NCT07220876iDose TR Administration in an Office-Based Surgery Setting
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07816692REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular Hypertension
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07675824A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular Hypertension
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07661329Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07075718A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases
RecruitingObservational studyHealthy volunteers welcome
Ages 20 to 79 · All sexes · Updated Aug 25, 2026 · NCT07780890Travoprost Intraocular Implant + iStent Infinite
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06066645Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)
RecruitingPhase 1
Ages 40 to 85 · All sexes · Updated May 19, 2026 · NCT07290244Adaptive Optics Retinal Imaging
RecruitingHealthy volunteers welcome
Ages 21 and older · All sexes · Updated May 8, 2026 · NCT05370287Direct vs Standard SLT for Glaucoma: A Noninferiority Trial
Recruiting
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT0740815424-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients
RecruitingPhase 4
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT07325240DSLT for Reducing Medication in Glaucoma
RecruitingObservational study
All ages · All sexes · Updated Apr 20, 2026 · NCT07390890A Trial of Hydrus Microstent Versus Goniotomy
Recruiting
Ages 40 to 85 · All sexes · Updated Mar 30, 2026 · NCT06289491Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT07495852Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT07217678Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT07400926Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone
RecruitingPhase 4
Ages 45 and older · All sexes · Updated Jan 21, 2026 · NCT06848946Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Nov 14, 2025 · NCT07228221Diagnostic Innovations in Glaucoma Study
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 24, 2025 · NCT00221897Direct Selective Laser Trabeculoplasty (DSLT) for Reducing Eye Pressure in Non-Caucasian Patients With Open Angle Glaucoma
Recruiting
Ages 18 and older · All sexes · Updated Aug 29, 2025 · NCT07147647From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.