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Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment

Recruiting

Pilot Study to Assess Safety, Tolerability and Efficacy of Virtual Reality in Cancer Patients

Who can join

Ages 18 to 90 · All sexes

Full eligibility criteria
Inclusion Criteria:

* History of cancer
* Age between 18 to 90 years
* Undergoing in-patient chemotherapy, bone marrow transplant (BMT), chimeric antigen receptor (CAR)-t, \& out-patient chemotherapy

Exclusion Criteria:

* History of bipolar disorder, major depression, bipolar disorder, anxiety disorder, post traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), psychotic disorder, schizophrenia, personality disorder, substance use disorder other than caffeine or tobacco. History of suicidal ideation or attempt
* History of treatment resistant depression, psychiatric hospitalization, syncope, transient ischemic attack (TIA), stroke, epilepsy, electroconvulsive therapy, benign positional vertigo, Meniere's disease

About the study

This clinical trial tests the safety, tolerability, and effectiveness of a virtual reality intervention to improve psychological symptom burden for cancer patients undergoing treatment. Virtual reality (VR) is a technology that allows users to experience and interact with three-dimensional, computer-generated environments that simulate the real world or imagined settings. The VR intervention consists of a preloaded with immersive environments designed to engage the senses through simulated sights and sounds. This may include a walk through of a serene forest, exploring vibrant coral reefs, swimming with dolphins, or standing at the base of a majestic waterfall. These environments are created to provide a relaxing and engaging experience. Completing the VR intervention may be a safe and effective way to improve quality of life, reduce anxiety, enhance focus, and promote healthy living for cancer patients undergoing treatment.

What is being tested

Sponsor: Mayo Clinic · Participants: 24 · Started: Oct 8, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07221409

Locations in the U.S.

FloridaMayo Clinic in Florida, Jacksonville

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.