Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)

Recruiting

Performance of Liver Stiffness Measurement (LSM) by FibroScan® for the Diagnosis of Elevated Central Venous Pressure (CVP)

Who can join

Ages 18 and older · All sexes

Full eligibility criteria

Inclusion Criteria:

1. Have read, understood, and signed the informed consent form (ICF)
2. Be ≥18 years of age at the time of screening
3. Have suspected or diagnosed acute or chronic HF and be scheduled to undergo right-sided cardiac catheterization

Exclusion Criteria:

1. Inability to consent
2. Chronic liver disease (self-reported alcohol use \>14 drinks/week in females and \>21 drinks/week in males), positive hepatitis C virus serology, positive hepatitis B surface antigen, autoimmune hepatitis, hemochromatosis, or cholestatic disease)
3. BMI \>40 kg/m2
4. Fontan-type circulation
5. Ascites
6. Heart transplantation
7. Pregnancy, breastfeeding, or intent to become pregnant during the study
8. Intent to donate/bank or retrieve eggs (ova, oocytes) or donate sperm during the study

About the study

This is a pivotal, global, prospective, cross-sectional, multicentric clinical investigation designed to explore a non-invasive, reliable alternative to invasive, catheter-based hemodynamic assessments, which are associated with procedural risks and limited applicability in certain participant populations.

What is being tested

FibroScan (device)
Right-sided Heart Catheterization (procedure)
Transthoracic echocardiography (procedure)
Blood Sample Analysis (biological)

Sponsor: Echosens · Participants: 149 · Started: Apr 23, 2026

Contact the study team

CAROLE MEILLEROUX, PharmD · Phone: +33622649277

Official record on ClinicalTrials.gov — NCT07222813

Locations in the U.S.

California	Keck Medicine of USC-Norris Healthcare Center - Transplant Clinic, Los Angeles (Not yet recruiting)
Minnesota	University of Minnesota, Minneota
South Carolina	Medical University of South Carolina, Charleston
Texas	University of Texas Southwestern Medical Center - Clinical Heart and Vascular Center - West Campus Building 3 Location, Dallas

Conditions

Heart Failure

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.