Home › Colorectal Cancer › NCT07224789

Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Adults (≥18 years old)
* Histologically confirmed colorectal cancer (Stage I-III)
* Availability of pre-treatment plasma samples
* Written informed consent provided

Exclusion Criteria:

* History of other active malignancies within the past 5 years
* Poor sample quality or hemolysis
* Inability to provide informed consent

About the study

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. This study aims to develop a non-invasive liquid biopsy assay using plasma-derived cell-free circular RNAs (cf-circRNAs) for early and accurate detection of colorectal cancer.

What is being tested

• cf-circRNA assay (diagnostic test)

Sponsor: City of Hope Medical Center · Participants: 600 · Started: Jan 15, 2025

Contact the study team

• Goel Ajay, PhD · Phone: 626-218-3452

Official record on ClinicalTrials.gov — NCT07224789

Locations in the U.S.

Conditions

• Colorectal Cancer

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.