Effects of Grape Consumption on the Immune-Gut Axis in Obesity
Recruiting
Effects of Grape Consumption on Immune and Gut Health in the Setting of Obesity
Who can join
Ages 18 to 60 · All sexes
Full eligibility criteria
Inclusion Criteria: * Age: 18-60 years * Obesity with BMI of 30-45 kg/m2 * Willingness to consume study foods * Consistent diet and activity patterns for 4 weeks * Weight stable (\<5kg change over last 3 months) * Non-smoker \> 1 year or more * Not currently consuming an extremely healthy diet Exclusion Criteria: * Study food allergies * Regular consumption of grapes or grape-derived products * Gastrointestinal disease and/or bariatric surgery * Uncontrolled hypertension and blood pressure \>180/110 * Diabetes * Illicit drug use * History of alcohol or drug abuse * Recent use of medications that affect immune function (e.g., corticosteroids) * Recent consumption of antibiotics, prebiotics, probiotics, symbiotics, or dietary supplements containing fiber or phytochemicals * Pregnant or lactating individuals * HIV positivity * Recent start of medications that affect metabolism or appetite * Drug therapy for coronary artery disease, peripheral artery disease, congestive
About the study
This study is investigating the benefits of whole freeze-dried grape powder consumption on the immune-gut axis in adults with obesity.
What is being tested
- Freeze-dried grape powder (other)
- Placebo powder (other)
Sponsor: University of Missouri-Columbia · Participants: 50 · Started: Dec 19, 2025
Contact the study team
- Jaapna Dhillon PhD, PhD · Phone: 573-884-2103
- Caitlyn Winn, MS · Phone: 207-210-8049
Official record on ClinicalTrials.gov — NCT07231484
Locations in the U.S.
| Missouri | University of Missouri-Columbia, Columbia |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.