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Diet and Motility in IBS

The Role of Diet and Gastrointestinal Motility in Irritable Bowel Syndrome (IBS)

Who can join

Ages 8 to 18 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

Cases:

1. Males and females age 8 - 18 years
2. Diagnosis of irritable bowel syndrome (IBS).
3. Parental/guardian permission (informed consent) and child assent

Controls:

1. Males and Females age 8-18 years
2. No diagnosis of abdominal pain disorder
3. Parental/guardian permission (informed consent) and child assent

Exclusion Criteria:

Cases:

1. Allergy to adhesives
2. Inability to cooperate with study design
3. Antibiotic intake in the past 4 weeks
4. Inflammatory gastrointestinal disorder diagnosis

Controls:

1. Allergy to adhesives
2. Inability to cooperate with study design
3. Antibiotic intake in the past 4 weeks
4. Inflammatory gastrointestinal disorder diagnosis

About the study

The goal of this observational study is to identify factors that influence symptoms in children with irritable bowel syndrome (IBS), to find ways to make diet treatments work better and possibly create personalized plans to help each child with IBS feel better. The main question it aims to answer is:

1. What types of food do the kids eat and how do these diets relate to their symptoms? 2. Is there any motility pattern that we can identify from the kids with or without IBS using a wearable patch? 3. What kinds of bacteria and chemicals are found in the gut and urine of children with IBS, and how are these linked to their IBS symptoms?

Participants will use the wearable patch, answer questionnaires, collect stool and urine samples, and recall their 24 hours dietary.

What is being tested

• Wireless Patch System (diagnostic test)

Sponsor: Children's Hospital of Philadelphia · Participants: 90 · Started: Jul 31, 2023

Contact the study team

• Alain Benitez, MD, MSTR · Phone: 215-590-1000

Official record on ClinicalTrials.gov — NCT07283341

Locations in the U.S.

Conditions

• Irritable Bowel Syndrome

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.