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Low-Tech Treatments for Obstructive Sleep Apnea

Myofunctional Therapy for Obstructive Sleep Apnea in U.S. Service Members With and Without Traumatic Brain Injury

Who can join

Ages 18 to 65 · All sexes

Inclusion Criteria:

* New diagnosis of OSA (AHI, ≥ 5) or failure of first-line OSA treatment;
* Willingness to forego first-line OSA treatment or stop current OSA treatment for 3 months;
* Ability to follow directions and perform the required exercises;
* Age between 18-65 yr.

Exclusion Criteria:

* Current use of OSA treatment;
* Medical comorbidities that require restricting fluid intake (e.g., dysphagia, renal disease, liver disease, hyponatremia);
* Severe nasal obstruction; 4) severe ankyloglossia; 4) craniofacial abnormality; 5) severe pulmonary disease; 6) severe post-traumatic stress disorder; 7) very severe insomnia; 8) body mass index (BMI) ≥30 kg/m2

About the study

The overall purpose of this study is to compare changes in sleep outcomes in people with obstructive sleep apnea (OSA) depending on their participation in one of two behavioral interventions; both involve drinking water and breathing. A second purpose is to compare outcomes between people who have sustained a traumatic brain injury (TBI) and those with no history of TBI. The main questions it aims to answer are whether sleep quality improves after 3-months of high-resistance versus low-resistance exercises, and whether people have different outcomes depending on their history of TBI.

What is being tested

• High-Resistance Breathing and Drinking Exercises (behavioral)
• Low-Resistance Breathing and Drinking Exercises (behavioral)

Sponsor: Uniformed Services University of the Health Sciences · Participants: 60 · Started: Jan 29, 2026

Contact the study team

• Nancy P. Solomon, Ph.D. · Phone: 301-319-7042

Official record on ClinicalTrials.gov — NCT07301710

Locations in the U.S.

Conditions

• Obstructive Sleep Apnea
• Traumatic Brain Injury

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.