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Collection of Samples From the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance

RecruitingObservational studyHealthy volunteers welcome

Collection of Samples From the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance (PROVE)

Who can join

Ages 45 to 84 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Arm A: Diagnosed with CRC
* Arm B: Undergoing screening with colonoscopy for CRC

Exclusion Criteria:

* Arm A: Undergoing treatment for CRC,
* Arm B: Past history of CRC

About the study

This study is designed to prospectively collect blood samples and clinical data from patients that have been newly diagnosed with colorectal cancer and scheduled for resection surgery but are pre cancer treatment, subjects who are NOT scheduled for surgery but have histological confirmation of CRC from the diagnostic colonoscopy and clinical staging (cTMN) is available and are pr e- treatment, and patients who are at average risk of colorectal cancer and who are scheduled for routine colonoscopy examinations.

Sponsor: Universal Diagnostics · Participants: 6,500 · Started: Jul 31, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT07310446

Locations in the U.S.

IllinoisGastroenterology and Internal Medicine Specialists, Lake Barrington

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.