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Telehealth-Adapted Compensatory Training and Intervention for Cognition

Telehealth-Adapted Compensatory Training and Intervention for Cognition for People With Mild Cognitive Impairment

Who can join

Ages 65 to 84 · All sexes

Inclusion Criteria:

* 65 years of age or older, less than 85 years
* Have the ability to speak and understand English
* Time and willingness to commit to the completion of this study
* Availability of a study partner (typically a relative, spouse, offspring, or roommate) for initial and post-intervention testing
* A global Clinical Dementia Rating scale (CDR) score of 0.5 and cognitive performance of \<26 on the Montreal Cognitive Assessment (MoCA) or \<19 on the MoCA-BLIND for categorization of MCI, as determined in the screening appointment.

Exclusion Criteria:

* Self-reported diagnosis of dementia or functional impairment that requires assistance
* Recent changes in medications for memory (i.e., prescribed or changed medications for memory within 30 days)
* Major psychiatric illness (schizophrenia, current substance dependence, or undertreated depression or anxiety), or 15-item Geriatric Depression Scale (GDS-15) score of eight or higher
* Hearing, vision, or motor deficits that would interfere with standardized cognitive assessment or participation in study interventions: e.g., inability to hear through headphones (with or without hearing aids). If vision is corrected with lenses to appropriate levels, then participant will be eligible
* No access to reliable, stable internet, OR
* Current participation in another cognitive training program or treatment study.

About the study

The goal of this clinical trial is to develop a five-week virtual cognitive training intervention for people with Mild Cognitive Impairment (MCI) based off an existing eight-week intervention. The main question it aims to answer is:

• Is five weeks of training as good as eight weeks in improving cognition, quality of life, daily functioning, and mood, and in reducing caregiver burden? Researchers will compare five weeks of cognitive training to eight weeks of training to see if the shorter version is as effective as the full training.

Participants will complete all activities virtually:

* Complete a screening visit with a study partner (typically a family member, roommate, or close friend) to determine eligibility to participate in the study * Complete some tests of memory and thinking and some questionnaires * Attend weekly two-hour group cognitive training sessions with a trained group leader, for five or eight weeks * Redo the questionnaires and tests of memory and thinking immediately after completing the training, and three months after completing the training

What is being tested

• Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (ME-CCT-MCI) (behavioral)
• Brief Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (bME-CCT-MCI) (behavioral)

Sponsor: University of Florida · Participants: 100 · Started: May 29, 2026

Contact the study team

• Cameron K Perrin, M.S. · Phone: 352-294-8765

Official record on ClinicalTrials.gov — NCT07366346

Locations in the U.S.

Conditions

• Mild Cognitive Impairment
• Dementia

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.