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Enhancing Brain And Mental Health Through Breathing Practice

Recruiting

Enhancing Brain And Mental Health Through Breathing Practice: Clinical Applications In Rural Adolescents With Psychiatric Symptoms (Breathing Study -Adolescent)

Who can join

Ages 12 to 17 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Adolescents between the ages of 12 and 17 who have been diagnosed with a major depressive disorder (mild or moderate) and/or an anxiety disorder.
* Participants may have co-occurring mild to moderate alcohol or drug use problems, provided these do not require immediate specialized treatment or crisis intervention.
* All participants must be receiving care at one of two participating MCHS outpatient psychiatry clinics and may reside in rural area (RUCA code 4-10) or non-rural area.
* Participants must be able to read and understand English, and both parental or guardian consent and adolescent assent will be required.

Exclusion Criteria:

* Current suicidal ideation or self-harm behavior requiring immediate clinical intervention
* Presence of severe psychiatric comorbidities such as psychosis, bipolar disorder, depression with psychotic features, severe alcohol and drug use, or eating disorders.
* Participants with significant cognitive impairment that would interfere with study participation.

About the study

The purpose of this study is to evaluate the feasibility of a structured breathing intervention in rural and non-rural adolescents diagnosed with anxiety and depression, recruited from outpatient pediatric and child/adolescent psychiatry clinics.

What is being tested

Sponsor: Mayo Clinic · Participants: 40 · Started: Feb 19, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07369752

Locations in the U.S.

MinnesotaMayo Clinic Health System-Albert Lea, Albert Lea
WisconsinMayo Clinic Health System-Eau Claire Clinic, Eau Claire

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.