Home › Chronic Kidney Disease › NCT07385651

Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage

Who can join

Ages 18 and older · All sexes

Participant inclusion criteria

1\. All adult single organ kidney transplant candidates on the waiting list at Vanderbilt University Medical Center (VUMC) will be eligible for enrollment.

Participant exclusion criteria

1. Kidney transplant candidates less than 18 years old
2. Kidney transplant candidates that decline consent
3. Transplant candidates listed for multi-organ transplant

Deceased donor organ inclusion criteria:

1. Donation after brain death or donation after circulatory death kidney donors, whose health care proxy has consented for donation and the possibility of research
2. Deceased donor kidneys that have been allocated to VUMC as a primary match offer prior to organ procurement will be eligible

Deceased donor organ exclusion criteria:

1. Donors whose health care proxy has declined consent for the possibility of research
2. Deceased donor kidneys that have been allocated to VUMC as a backup offer
3. Deceased donor kidneys that have been allocated to VUMC as a post procurement offer
4. Deceased donor kidneys that have already been placed on ice

About the study

The goal of this clinical trial is to test how storage temperature of deceased donor kidneys affects kidney function after transplant in adult patients receiving a kidney transplant.

The main question it aims to answer is:

• Do patients that receive a kidney transplant stored at 10 °C have improved post-transplant kidney function? Researchers will compare patients who receive kidneys stored at 10 °C versus kidneys stored at 4°C (on ice, i.e. conventional storage) to see if kidneys stored at 10 °C have improved function.

Participants will:

* Be made aware of and consent to receive a kidney transplant that had been stored at 10 °C * Have their urine collected 24 hours after surgery to be analyzed for research

What is being tested

• 10˚C deceased donor kidney storage using Traferox XPort (device)

Sponsor: Vanderbilt University Medical Center · Participants: 30 · Started: Nov 18, 2024

Contact the study team

• W. Christian Crannell, MD · Phone: 615-322-5000

Official record on ClinicalTrials.gov — NCT07385651

Locations in the U.S.

Conditions

• Chronic Kidney Disease

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.