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Peripheral Venous Pressure (PVP) Trial

Recruiting

Reducing the Length of Stay and Incidence of Rehospitalization in Heart Failure Patients by Measuring Peripheral Venous Pressure; a Randomized Clinical Trial

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Patients with minimum 3-month history of Congestive Heart Failure admitted to Aurora St. Luke's Medical Center with acute decompensation
* English speaking only

Exclusion Criteria:

* Patients who do not already have a peripheral IV line inserted
* Patients whose IV line cannot be transduced
* Patients with current or past vein thrombosis in the arm used to measure the pressure or with history of recurrent (\>1) pulmonary embolism
* Patients with active thrombophlebitis in the arm
* Patients who have experienced a major cardiovascular event (myocardial infarction, stroke, etc.) ≤2 months prior to the admission date
* Patients who have received an implanted cardiac resynchronization device (pacemaker or ICD) ≤3 months prior to admission date
* Patients enrolled in other cardiovascular research studies.
* Patients with a clinical condition that the investigator believes may not allow the patient to complete the study, at the discretion of the investigator. Examples of conditions that may apply include severe stenotic valvular disease, isolated right ventricle failure, precapillary pulmonary hypertension, hypertrophic obstructive cardiomyopathy, implanted left ventricular assist device, history of heart transplantation, clinical diagnosis of cardiogenic shock, any left-to-right shunt
* Patients with congenital heart disease or mechanical right heart valve(s)
* Planned heart surgery and/or coronary intervention during hospitalization
* Patients expected to receive heart transplant within 6 months of admission
* IV cannula smaller than 22G
* Patients who are pregnant and/or lactating
* Patients who are unable to provide informed consent
* Patients who are intubated

About the study

The purpose of the study is to determine if there is a reduction in the length of stay and rates of rehospitalization for patients diagnosed with congestive heart failure when physicians are provided daily measurements of peripheral venous pressure versus no daily measurements of peripheral venous pressure.

What is being tested

Sponsor: Wake Forest University Health Sciences · Participants: 600 · Started: Jul 27, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07400042

Locations in the U.S.

WisconsinAurora St. Luke's Medical Center, Milwaukee

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.