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Supraglottic Airway for Resuscitation in Preemies
Supraglottic Airway Interface for Positive Pressure Ventilation During Delivery Room Resuscitation of Premature Infants: A Pilot Feasibility Trial
Who can join
0 Days – 1 Day · All sexes
Full eligibility criteria
Inclusion Criteria: * Gestational age 29 0/7 to 33 6/7 weeks at birth * Estimated fetal weight \>/= 1000 grams at birth * Clinical decision to initiate PPV * Parental informed consent Exclusion Criteria: * Major anomalies or aneuploidy * Palliative care planned or considered * Not resuscitated in the infant resuscitation room
About the study
The goal of this single-arm intervention trial is to learn whether using a supraglottic airway (SA) as the primary interface for positive pressure ventilation (PPV) is feasible during delivery room resuscitation of premature infants. This study will be conducted in premature infants born between 29 0/7 and 33 6/7 weeks' gestation who require PPV at birth.
The main question it aims to answer is: Is it feasible to use a supraglottic airway as the primary interface to provide effective PPV during delivery room resuscitation in 29 0/7 to 33 6/7 weeks' gestation premature infants?
Participants will (1)Be screened prenatally and have informed consent obtained from the birth parent prior to delivery; (2)Be rescreened for eligibility on the day of delivery before receiving the study intervention; (3)Receive PPV using a supraglottic airway as the primary ventilation interface if resuscitation is required at birth; and (4)Have clinical and procedural data collected during delivery room resuscitation and for up to 24 hours after birth.
What is being tested
- Supraglottic Airway (other)
Sponsor: University of Pennsylvania · Participants: 20 · Started: Mar 13, 2026
Contact the study team
- Sura Lee · Phone: 215-873-9339
Official record on ClinicalTrials.gov — NCT07419438
Locations in the U.S.
| Pennsylvania | Hospital of the University of Pennsylvania, Philadelphia |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.