🔎 Trials Near Me

Home › Overweight › NCT07428187

Snacking Effects on the Brain Response to Foods and Satiety During Dieting

Recruiting

Who can join

Ages 25 to 45 · All sexes

Full eligibility criteria
Inclusion Criteria:

* 25-45 years old
* BMI at least 27 kg/m2
* Comfortable completing a weight-loss intervention\\
* Willing to consume a daily snack of either walnuts or pretzels

Exclusion Criteria:

* Nut or wheat allergy
* History of bariatric surgery
* Current eating disorder
* Current illicit substance use
* Current pregnancy, lactation (or less than 3 months after stopping lactation), or less than 6 months postpartum
* Uncontrolled hypertension (\>160/100 mmHg)
* Significant endocrine/metabolic disease kidney disease, liver disease, or blood disease that would be anticipated to affect study results
* Taking injectable medications, sulfonylureas, or meglitinides for diabetes treatment
* Taking weight-loss medications, or steroids within \~3 months prior to study participation (e.g., GLP-1 receptor agonists)
* Significant mental health changes within \~3 months prior to study participation (e.g., medication adjustments, new psychiatric diagnoses, hospitalization relating to mental health concerns)
* Neurological illnesses or injury that would be anticipated to affect MRI data
* Weight change greater than 10% within 3 months prior to study participation
* Currently participating in another weight-loss study
* Not comfortable eating the study-provided meals (with allowances for dietary preferences) and/or following a highly restrictive diet (e.g., vegan)
* MRI-specific exclusion criteria (e.g., metal in the body, weight \>500 lbs

About the study

This study plans to learn more about how different types of snacks may affect brain processes relating to eating behaviors during a diet intervention.

What is being tested

Sponsor: University of Colorado, Denver · Participants: 70 · Started: Mar 5, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07428187

Locations in the U.S.

ColoradoUniversity of Colorado Anschutz Medical Campus, Aurora

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.