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ACT With CF Self-Help Toolkit
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * 18 years or older * Existing diagnosis of cystic fibrosis * PHQ-9 score \>4 or GAD-7 score \>4 Exclusion Criteria: * History of suicide attempts or acute suicidal ideation on clinical assessment * Presence of psychotic disorder or symptoms * Presence of psychiatric disorders that interfere with participation in the study, judged by the study or treating clinician * Presence of other medical conditions that interfere with participation in the study, judged by the study or treating clinician
About the study
Acceptance and Commitment Therapy (ACT) tailored to meet the needs of adults living with cystic fibrosis (ACT with CF) is a newer form of talk therapy that has been shown to reduce anxiety \& depression and improve psychological flexibility, and value-based living. The investigators are now trying to find out whether a self-help version of this treatment (ACT with CF - Self Help Toolkit) is also effective in reducing anxiety and depression and improving psychological flexibility and value-based living in adults with CF.
Adults with cystic fibrosis are at increased risk for anxiety and depression. This study examines whether a patient-facing therapy, ACT with CF - Self Help Toolkit can help to reduce anxiety and depression among adults with CF. This treatment can be accessed on the participant's smartphone.
What is being tested
- ACT with CF Self-Help Toolkit (behavioral)
- Waitlist (other)
Sponsor: Thomas Jefferson University · Participants: 60 · Started: Jan 20, 2026
Contact the study team
- Virginia O'Hayer, PhD · Phone: 919-943-6738
Official record on ClinicalTrials.gov — NCT07436351
Locations in the U.S.
| Pennsylvania | Thomas Jefferson University Hospital, Philadelphia |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.