Home › Chronic Kidney Disease › NCT07446296
Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
KINETIC -- Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
Who can join
Ages 60 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * be at least 60 years old * receive transplant care at Penn Medicine * be on the kidney transplant waiting list * speak and comprehend English * be able to walk * have at least one physical function limitation OR at least one frailty metric * have access to a device capable of connecting to the Internet and downloading an application * be able to provide written informed consent * be cleared for participant via the Physical Activity Readiness Questionnaire (PARQ) verified against medical record or via written medical clearance from a clinician Exclusion Criteria: * Have had a myocardial infarction or a stroke in the 3 months immediately prior to enrollment * Be unable to self-monitor with study devices (i.e., have a condition such as dementia) * Not cleared by PARQ or receive written medical clearance to exercise * Participate in another physical activity study * Have any other reason they do not expect to be able to complete the study
About the study
The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant. The study will also learn how acceptable and useful this program is for participants.
The main questions it aims to answer are:
* Can a remote exercise program be delivered successfully to people on the kidney transplant waiting list? * Do participants follow the exercise program and wear a physical activity tracker as asked? * Is the program safe and well tolerated?
Researchers will compare two groups to see if the exercise program leads to higher physical activity and better physical function:
* Usual pre-transplant care with a physical activity tracker * Usual pre-transplant care plus an online exercise program
Participants will:
* Wear a wrist activity tracker to measure daily physical activity * Complete a one-week baseline period before being assigned to a study group * Be randomly assigned (like flipping a coin) to one of two groups * If assigned to the exercise group, take part in online exercise classes at home for 12 weeks with reminders and feedback, and then another 12 weeks without reminders and feedback * Answer questionnaires about their health, activity, and experience in the study
This study may help researchers learn how to better support people waiting for kidney transplant through safe, home-based exercise programs.
What is being tested
- Exercise Rehabilitation Program with Physical Activity Tracker (behavioral)
- Active control (other)
Sponsor: University of Pennsylvania · Participants: 60 · Started: Mar 24, 2026
Contact the study team
- Sarah Schrauben, MD, MSCE · Phone: 2156628730
Official record on ClinicalTrials.gov — NCT07446296
Locations in the U.S.
| Pennsylvania | Perelman Center for Advanced Medicine, Philadelphia |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.