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Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology

RecruitingHealthy volunteers welcome

Development and Assessment of Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
In order to participate in this study a subject must meet all of the eligibility criteria outlined below.

Inclusion Criteria:

Providers only

* ≥18 years
* Peer-review attendees at participating clinics

Patients only

* ≥18 years
* All patients with prostate cancer radiation therapy cases treated at participating sites (no intervention delivered to patients)

Exclusion Criteria:

Providers only

• Providers unwilling/unable to comply with study procedures; sites unable to implement the workflow or provide required outcomes.

Patients and Providers

• Has dementia, altered mental status, or any psychiatric or co-morbid condition prohibiting the understanding or rendering of informed consent

About the study

This prospective study will test artificial intelligence (AI) and machine learning (ML) decision support tools. This tool is designed to help doctors, physicists and other staff during pre-treatment peer review, a step where treatment plans are checked before a patient begins care.

The system highlights summaries showing how different providers may vary in their treatment planning (provider-variability summaries) and points out the best signals or warning signs to look for (optimal cues). By drawing attention to these patterns and cues, the tool aims to help reviewers spot possible treatment-planning mistakes earlier, reduce the chance of errors, and improve overall patient safety.

What is being tested

Sponsor: UNC Lineberger Comprehensive Cancer Center · Participants: 207 · Started: Jun 22, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07463833

Locations in the U.S.

North CarolinaUniversity of North Carolina at Chapel Hill, Department of Radiation Oncology, Chapel Hill

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.