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STABLE Pilates for Hypermobility

Recruiting

Pilates for Hypermobility: A Pilot Feasibility Study

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* ≥ 18 years old;
* Self-reported hypermobility with confirmed or suspected diagnosis of hEDS/HSD;
* Self-reported persistent pain ≥ 3 months;
* A minimum of 3/10 self-reported pain intensity in the past week
* Able to get on and off the floor without assistance;
* Able to communicate fluently in English; and
* Able to provide written, informed consent

Exclusion Criteria:

* Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min/week over the past 6 months;
* Recent surgery or acute bone, joint or nerve injury (\<6 months);
* Have a history of a severe or progressive neurological or movement disorder;
* Pregnant, planning to become pregnant during the study, or currently breast feeding;
* Unable to get on and off the floor without assistance;
* Unable to complete study procedures due to cognitive impairment;
* Unable to provide written, informed consent; or
* Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.

About the study

This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.

What is being tested

Sponsor: Brigham and Women's Hospital · Participants: 100 · Started: Jul 9, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07464093

Locations in the U.S.

MassachusettsBrigham and Women's Hospital, Chestnut Hill

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.